Abstract
In this prospective cohort of 1,012 Swiss hospital employees, 3 different assays were used to screen serum for SARS-CoV-2 antibodies. Seropositivity was 1%; the positive predictive values of the lateral-flow immunoassay were 64% (IgG) and 13% (IgM). History of fever and myalgia most effectively differentiated seropositive and seronegative participants.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibodies, Viral / blood*
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COVID-19 / blood
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COVID-19 / diagnosis*
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COVID-19 / virology
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Female
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Humans
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Immunoassay
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Immunoglobulin G / blood*
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Immunoglobulin M / blood*
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Male
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Middle Aged
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Personnel, Hospital / statistics & numerical data*
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Prevalence
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Prospective Studies
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SARS-CoV-2
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Seroepidemiologic Studies
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Switzerland / epidemiology
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Young Adult
Substances
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Antibodies, Viral
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Immunoglobulin G
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Immunoglobulin M