Two novel HLA-DRB1 alleles, DRB111:261 and DRB113:286 identified by sequencing in Brazilian individuals

HLA. 2020 Dec;96(6):744-745. doi: 10.1111/tan.14103. Epub 2020 Oct 19.

Authors

Silvia B D Marques¹, Edilaine G Guariento¹, Jeane E L Visentainer², Evaldo Nascimento^{3

4}, Raquel A Fabreti-Oliveira^{3

4}

Affiliations

¹ Hemocentro of Campinas, Histocompatibility Laboratory, University of Campinas - Unicamp, Campinas, SP, Brazil.
² Laboratory of Immunogenetics, Department of Basic Health Sciences, State University of Maringá, Paraná, Brazil.
³ Faculty of Medical Sciences, Belo Horizonte, Minas Gerais, Brazil.
⁴ IMUNOLAB Laboratory of Histocompatibility, Belo Horizonte, Minas Gerais, Brazil.

PMID: 33043627
DOI: 10.1111/tan.14103

Abstract

Two novel HLA alleles DRB1*11:261 and DRB1*13:286 have nonsynonymous mutations in exon 2.

Keywords: Brazilian population; HLA polymorphism; SNP.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Brazil
Exons / genetics
HLA-DRB1 Chains* / genetics
Humans

Substances

HLA-DRB1 Chains