Spontaneous Regression of High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements: Case Report and Literature Review

Clin Lymphoma Myeloma Leuk. 2021 Feb;21(2):e120-e125. doi: 10.1016/j.clml.2020.09.006. Epub 2020 Sep 23.

Authors

Lauren M Stanoszek¹, Lauren B Smith¹, Karen Grajewski², John C Reneau³, Ryan Wilcox⁴, Anamarija M Perry⁵

Affiliations

¹ Department of Pathology, University of Michigan, Ann Arbor, MI.
² Department of Radiology, University of Michigan, Ann Arbor, MI.
³ Department of Internal Medicine, Ohio State University, Columbus, OH.
⁴ Department of Internal Medicine, University of Michigan, Ann Arbor, MI.
⁵ Department of Pathology, University of Michigan, Ann Arbor, MI. Electronic address: [email protected].

PMID: 33060050
DOI: 10.1016/j.clml.2020.09.006

No abstract available

Keywords: Aggressive lymphoma; Diffuse large B-cell lymphoma; Double expressor lymhoma; Double-hit lymphoma; Lymphoma resolution.

Publication types

Case Reports
Review

MeSH terms

Adult
Biopsy
Bone Marrow / pathology
Gene Rearrangement
Humans
Lymphoma, B-Cell / diagnosis*
Lymphoma, B-Cell / genetics
Lymphoma, B-Cell / pathology
Male
Neoplasm Grading
Positron Emission Tomography Computed Tomography
Proto-Oncogene Proteins c-bcl-2 / genetics*
Proto-Oncogene Proteins c-myc / genetics*
Remission, Spontaneous

Substances

BCL2 protein, human
MYC protein, human
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogene Proteins c-myc