Estimation of intracranial volume: A comparative study between synthetic MRI and FSL-brain extraction tool (BET)2

Masami Goto; Akifumi Hagiwara; Ayumi Kato; Shohei Fujita; Masaaki Hori; Koji Kamagata; Hidenori Sugano; Hajime Arai; Shigeki Aoki; Osamu Abe; Hajime Sakamoto; Yasuaki Sakano; Shinsuke Kyogoku; Hiroyuki Daida

doi:10.1016/j.jocn.2020.07.024

Estimation of intracranial volume: A comparative study between synthetic MRI and FSL-brain extraction tool (BET)2

J Clin Neurosci. 2020 Sep:79:178-182. doi: 10.1016/j.jocn.2020.07.024. Epub 2020 Aug 6.

Authors

Masami Goto¹, Akifumi Hagiwara², Ayumi Kato³, Shohei Fujita⁴, Masaaki Hori⁵, Koji Kamagata², Hidenori Sugano⁶, Hajime Arai⁶, Shigeki Aoki², Osamu Abe⁷, Hajime Sakamoto⁸, Yasuaki Sakano⁸, Shinsuke Kyogoku⁸, Hiroyuki Daida⁸

Affiliations

¹ Department of Radiological Technology, Faculty of Health Science, Juntendo University, 2-1-1 hongo, bunkyo-ku, Tokyo 113-8421, Japan. Electronic address: [email protected].
² Department of Radiology, Juntendo University School of Medicine, Japan.
³ Department of Radiology, Juntendo University School of Medicine, Japan; Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Japan.
⁴ Department of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Japan.
⁵ Department of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Toho University Omori Medical Center, Japan.
⁶ Department of Neurosurgery, Juntendo University School of Medicine, Japan.
⁷ Department of Radiology, Graduate School of Medicine, The University of Tokyo, Japan.
⁸ Department of Radiological Technology, Faculty of Health Science, Juntendo University, 2-1-1 hongo, bunkyo-ku, Tokyo 113-8421, Japan.

PMID: 33070892
DOI: 10.1016/j.jocn.2020.07.024

Abstract

Brain extraction represents an important step in numerous neuroimaging analyses. The brain extraction tool (BET)2 is a widely used deformable model-based approach for extraction of intracranial volume (ICV). The aim of this study is to estimate the ICV extraction accuracy using synthetic MR(SyMRI) method and BET2 in healthy adult participants and patients with Sturge-Weber Syndrome (SWS), including infants. 'Quantification of relaxation times and proton density by multi-echo acquisition of saturation recovery with turbo-spin-echo readout' (QRAPMASTER) with a 3.0 T magnetic resonance image (MRI) system was used for data acquisition. Statistical evaluations were performed with linear regression analysis and the Jaccard similarity coefficient (J). ICV extraction accuracy with synthetic MR method is found to be higher than BET2, for both aged healthy participants and SWS.

Keywords: Brain extraction; FSL; QRAPMASTER; Sturge-Weber Syndrome; Synthetic MRI.

Publication types

Comparative Study

MeSH terms

Adolescent
Adult
Brain / diagnostic imaging*
Child
Child, Preschool
Female
Healthy Volunteers
Humans
Image Interpretation, Computer-Assisted / methods*
Infant
Magnetic Resonance Imaging / methods
Male
Neuroimaging / methods*
Software*
Sturge-Weber Syndrome / diagnostic imaging*