Objective: To determine whether body mass index (BMI) affects intrauterine insemination treatment success.
Design: Retrospective cohort study.
Setting: Academic medical center.
Patient(s): A total of 3,217 intrauterine insemination treatment cycles in 1,306 patients.
Intervention(s): None.
Main outcome measure(s): Primary outcome was live birth rate stratified by BMI. Secondary outcomes included rates of clinical pregnancy (defined as an intrauterine pregnancy with a heartbeat present on ultrasound), multiple gestation, biochemical pregnancy, missed abortion, ectopic, and spontaneous abortion.
Result(s): Women with BMI 25 to 29.99 kg/m2 or ≥30 kg/m2 were equally likely to have a live birth as women of normal BMI. Women with BMI ≥30 kg/m2 did have a higher likelihood of biochemical pregnancy than women with normal BMI.
Conclusion(s): A BMI between 25 and 29.99 kg/m2 or ≥30 kg/m2 does not appear to have a negative effect on live birth after intrauterine insemination. Obesity may be associated with a higher risk of biochemical pregnancy after intrauterine insemination.
Keywords: Body mass index; IUI; artificial insemination; infertility; obesity; overweight.
Copyright © 2020 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.