The effect of Ulva lactuca and Sargassum hemiphyllum var. chinense on arsenic metabolites and enzymes in broilers

Ching-Chi Hung; Bao-Ji Chen; Jiunn-Wang Liao; Yung-Ping Tai; Ching-Yi Chen

doi:10.1016/j.foodchem.2020.128346

The effect of Ulva lactuca and Sargassum hemiphyllum var. chinense on arsenic metabolites and enzymes in broilers

Food Chem. 2021 Apr 16:342:128346. doi: 10.1016/j.foodchem.2020.128346. Epub 2020 Oct 12.

Authors

Ching-Chi Hung¹, Bao-Ji Chen², Jiunn-Wang Liao³, Yung-Ping Tai⁴, Ching-Yi Chen⁵

Affiliations

¹ Livestock Research Institute, Council of Agriculture, Executive Yuan. No. 112, Muchang, Xinhua Dist., Tainan City 71246, Taiwan; Department of Animal Science and Technology, National Taiwan University, No. 50, Lane 155, Sec 3, Keelung Rd, Taipei, Taiwan. Electronic address: [email protected].
² Department of Animal Science and Technology, National Taiwan University, No. 50, Lane 155, Sec 3, Keelung Rd, Taipei, Taiwan. Electronic address: [email protected].
³ Graduate Institute of Veterinary Pathobiology, National Chung Hsing University, No. 145, Xingda Rd, Taichung, Taiwan. Electronic address: [email protected].
⁴ Livestock Research Institute, Council of Agriculture, Executive Yuan. No. 112, Muchang, Xinhua Dist., Tainan City 71246, Taiwan. Electronic address: [email protected].
⁵ Department of Animal Science and Technology, National Taiwan University, No. 50, Lane 155, Sec 3, Keelung Rd, Taipei, Taiwan. Electronic address: [email protected].

PMID: 33077282
DOI: 10.1016/j.foodchem.2020.128346

Abstract

This study investigated the effect of seaweed supplementation (Ulva lactuca (UL) or Sargassum hemiphyllum var. chinense (SHC)) on the distribution and metabolites of As in broiler breasts. Broilers fed 5% UL or 5% SHC ingested 1.4- or 78- fold greater total As than birds fed the control diet. The majority of As species were arsenate in the SHC feed and dimethylarsinic acid in breasts from chicks fed the SHC-containing diet. Arsenate and arsenobetaine were the dominant metabolites in the UL-containing feed, and arsenobetaine was the major metabolite in breasts from chicks fed the UL-containing diet. Feeding SHC enhanced hepatic S-adenosyl-methionine and arsenic methyltransferase, whereas feeding UL elevated renal arsenic methyltransferase. Taken together, considerable variation in the profiles of As species and As metabolites existed in broilers fed seaweed. The use of SHC-containing feeds in poultry production should be approached cautiously because of the potential accumulation of inorganic As species in chicken breasts.

Keywords: 4-Hydroxyphenylarsonic acid (PubChem CID:7373); Ammonium carbonate (PubChem CID: 517111); Arsenate (PubChem CID: 234); Arsenic methyltransferase; Arsenic species; Arsenobetaine (PubChem CID: 47364); Arsenocholine bromide (PubChem CID: 153366); Asenite (PubChem CID: 443495); Broiler; Bromelain (PubChem CID: 44263865, Sigma-Aldrich, USA); Dimethylarsinic acid (PubChem CID: 2513); Methylarsonic acid (PubChem CID: 23664719); Roxarsone (PubChem CID: 5104); S-adenosyl methionine; Sargassum hemiphyllum; Seaweed; Ulva lactuca; p-Arsanilic acid (PubChem CID: 7389).

MeSH terms

Animals
Arsenic / metabolism*
Chickens / metabolism*
Diet
Sargassum / metabolism*
Ulva / metabolism*
Vegetables / metabolism

Substances

Arsenic