An in vitro determination of antibacterial effect of silver nanoparticles gel as an intracanal medicament in combination with other medicaments against Enterococcus fecalis

J Conserv Dent. 2019 Sep-Oct;22(5):479-482. doi: 10.4103/JCD.JCD_113_20. Epub 2020 Aug 4.

Abstract

Aim: The main aim of the study is to compare the antibacterial effect of Silver nanoparticle gel alone and combination of silver nanoparticle gel with various medicaments.

Materials and methods: Intracanal dressings: Group 1 -Silver Nanocure gel, Group 2 - Silver Nanocure gel+ Cavisept gel(1:1),Group 3- Silver Nanocure gel+ Aveu-Cal gel(1:1) ,Group 4 - Silver Nanocure gel +Cavisept gel +Aveu-Cal gel(1:1:1) were taken on a culture plate inoculated with E.faecalis. Antibacterial activity was assessed using Agar diffusion test and results were noted as diameter of growth inhibition zone.

Statistical analysis: Student t -test was used to analyse results.

Results: The diameter of combination of Silver nanocure gel+Cavisept +Aveu-Cal gel(1:1:1) was highest in comparison to other medicaments tested.

Conclusion: Intracanal dressing with a combination of all the three {Silver nanocure gel+Cavisept +Aveu-Cal gel(1:1:1) } is the best treatment for elimination of highly resistant Enterococcus faecalis in root canals.

Keywords: Agar diffusion test; inhibition zone; medicaments.