Folliculotropic mycosis fungoides driven by DOCK8 immunodeficiency syndrome

Belen Rubio-Gonzalez; Ilona J Frieden; Timothy H McCalmont; Morna Dorsey; Tracy Funk; Laura B Pincus

doi:10.1111/pde.14424

Folliculotropic mycosis fungoides driven by DOCK8 immunodeficiency syndrome

Pediatr Dermatol. 2021 Jan;38(1):229-232. doi: 10.1111/pde.14424. Epub 2020 Oct 25.

Authors

Belen Rubio-Gonzalez¹, Ilona J Frieden², Timothy H McCalmont^{1

2}, Morna Dorsey³, Tracy Funk⁴, Laura B Pincus^{1

2}

Affiliations

¹ Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
² Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.
³ Division of Pediatric Allergy, Immunology and Bone Marrow Transplantation, Benioff Children's Hospital, University of California San Francisco, San Francisco, CA, USA.
⁴ Department of Dermatology, Oregon Health and Science University, Portland, OR, USA.

PMID: 33099799
DOI: 10.1111/pde.14424

Abstract

DOCK8 immunodeficiency syndrome (DIDS) represents a rare primary immunodeficiency associated with cutaneous viral infections, allergy, and increased risk of malignancy. We report a case of folliculotropic mycosis fungoides with spontaneous resolution occurring in a patient with DIDS.

Keywords: DOCK8 deficiency; cutaneous T-cell lymphoma; folliculotropic mycosis fungoides.

Publication types

Case Reports

MeSH terms

Guanine Nucleotide Exchange Factors
Humans
Immunologic Deficiency Syndromes* / complications
Immunologic Deficiency Syndromes* / diagnosis
Mycosis Fungoides* / complications
Mycosis Fungoides* / diagnosis
Skin Neoplasms* / complications
Skin Neoplasms* / diagnosis

Substances

DOCK8 protein, human
Guanine Nucleotide Exchange Factors