Long-Term Outcomes of Robotic Thymectomy in Patients With Thymic Epithelial Tumors

Ann Thorac Surg. 2021 Aug;112(2):430-435. doi: 10.1016/j.athoracsur.2020.09.018. Epub 2020 Oct 29.

Abstract

Background: The long-term outcomes of robotic thymectomy for thymic epithelial tumors (TETs) are not well known, even though the early postoperative outcomes have improved. This study aimed to report the long-term survival and recurrence in patients with TETs who underwent robotic thymectomies.

Methods: A total of 158 patients who underwent robotic thymectomy for TET and who were followed-up for more than 1 year were included in the study. The median follow-up time was 43 (interquartile range, 40) months, and 156 (98%) patients were followed completely until the end of the study period.

Results: The mean age of the patients was 55.7 ± 12.7 years, and the mean size of the tumor was 4.6 ± 2.1 cm. There was no postoperative mortality and postoperative complications occurred in 7 (4.4%) patients. The median length of the postoperative hospital stay was 2 (interquartile range, 1-20) days. Thymoma was the most common cell type (n = 132, 84%), and thymic carcinoma (n = 24, 15%) and neuroendocrine tumors (n = 2, 1%) were the next most common types. Advanced stages more than stage III were identified in 15 patients (stage IIIA: n = 7, 4%; stage IVA: n = 5, 3%; and stage IVB: n = 3, 2%). The 5-year disease-specific survival was 100% in thymoma and 95% in thymic carcinoma. The 5-year recurrence-free survival was 94% in thymoma and 79% in thymic carcinoma.

Conclusions: Robotic thymectomy could achieve favorable long-term survival and recurrence rates, comparable to open or thoracoscopic thymectomy.

MeSH terms

  • Female
  • Follow-Up Studies
  • Humans
  • Length of Stay / trends
  • Male
  • Middle Aged
  • Neoplasms, Glandular and Epithelial / surgery*
  • Retrospective Studies
  • Robotic Surgical Procedures / methods*
  • Thymectomy / methods*
  • Thymus Neoplasms / surgery*
  • Time Factors
  • Treatment Outcome

Supplementary concepts

  • Thymic epithelial tumor