Clonal replacement of meticillin-resistant Staphylococcus aureus during repeated outbreaks in a long-term care facility

J Hosp Infect. 2021 Jan:107:23-27. doi: 10.1016/j.jhin.2020.10.023. Epub 2020 Nov 1.

Abstract

Meticillin-resistant Staphylococcus aureus (MRSA) is common among residents of long-term care facilities (LTCFs). Analysing the spa types of 22 isolates, mostly bloodstream infections (BSI), revealed five temporally distinct clonal outbreaks occurring in one ward of our local LTCF between 2012 and 2019. Each clone caused episodes of BSI for several months until replaced by another clone. A high MRSA carriage rate of 32% among healthcare workers in this ward was documented during the investigation of the 2019 outbreak. Clonal replacement of MRSA and the role of healthcare workers in transmission are discussed.

Keywords: Clonal replacement; Long-term care facility; Meticillin-resistant Staphylococcus aureus; Outbreak; spa type.

MeSH terms

  • Carrier State / epidemiology
  • Disease Outbreaks*
  • Health Personnel
  • Humans
  • Long-Term Care*
  • Methicillin-Resistant Staphylococcus aureus*
  • Staphylococcal Infections* / epidemiology