Multimodality lymphatic imaging of postoperative chylothorax in an infant with Noonan syndrome: a case report

Eur J Med Res. 2020 Nov 4;25(1):55. doi: 10.1186/s40001-020-00455-w.

Abstract

Background: Chylothorax is a rare complication of pediatric cardiac operations that occurs more frequently in children with Noonan syndrome, a genetic disorder associated with cardiac defects and lymphatic anomalies.

Case presentation: We report a case of postoperative chylothorax in a 6-month-old infant with Noonan syndrome where multimodality lymphatic imaging guided management was followed. Drainage patterns of the lymphatic capillaries in the lower and upper extremities were visualized during near-infrared fluorescence lymphatic imaging (NIRFLI). Dynamic magnetic resonance lymphangiography (MRL) further identified the site of leakage in the thoracic duct and subsequently guided surgical intervention.

Conclusions: Application of multimodality imaging allows for greater individualization of treatment and should be considered in patients with complex cases such as those with syndromes associated with a higher incidence of chylothorax. IRB Number: HSC-MS-13-0754, December 10, 2013.

Keywords: Chylothorax; MRL; NIRFLI; Noonan syndrome.

Publication types

  • Case Reports

MeSH terms

  • Chylothorax / diagnostic imaging*
  • Female
  • Humans
  • Infant
  • Lymphatic Vessels / diagnostic imaging
  • Lymphedema / complications
  • Lymphedema / diagnostic imaging
  • Lymphography / methods
  • Multimodal Imaging / methods*
  • Noonan Syndrome / complications
  • Noonan Syndrome / diagnostic imaging*
  • Noonan Syndrome / surgery*
  • Postoperative Complications / diagnostic imaging*