External validation of a prediction model on vaginal birth after caesarean in a The Netherlands: a prospective cohort study

J Perinat Med. 2020 Nov 6;49(3):357-363. doi: 10.1515/jpm-2020-0308. Print 2021 Mar 26.

Abstract

Objectives: Discussing the individual probability of a successful vaginal birth after caesarean (VBAC) can support decision making. The aim of this study is to externally validate a prediction model for the probability of a VBAC in a Dutch population.

Methods: In this prospective cohort study in 12 Dutch hospitals, 586 women intending VBAC were included. Inclusion criteria were singleton pregnancies with a cephalic foetal presentation, delivery after 37 weeks and one previous caesarean section (CS) and preference for intending VBAC. The studied prediction model included six predictors: pre-pregnancy body mass index, previous vaginal delivery, previous CS because of non-progressive labour, Caucasian ethnicity, induction of current labour, and estimated foetal weight ≥90th percentile. The discriminative and predictive performance of the model was assessed using receiver operating characteristic curve analysis and calibration plots.

Results: The area under the curve was 0.73 (CI 0.69-0.78). The average predicted probability of a VBAC according to the prediction model was 70.3% (range 33-92%). The actual VBAC rate was 71.7%. The calibration plot shows some overestimation for low probabilities of VBAC and an underestimation of high probabilities.

Conclusions: The prediction model showed good performance and was externally validated in a Dutch population. Hence it can be implemented as part of counselling for mode of delivery in women choosing between intended VBAC or planned CS after previous CS.

Keywords: caesarean section; external validation; prediction model; vaginal birth after caesarean.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Body Mass Index
  • Clinical Reasoning*
  • Decision Support Techniques*
  • Delivery, Obstetric / methods*
  • Female
  • Humans
  • Labor Presentation
  • Labor, Induced / methods
  • Netherlands / epidemiology
  • Pregnancy
  • Pregnancy, High-Risk
  • Prenatal Care / methods*
  • Prognosis
  • Risk Adjustment / methods
  • Trial of Labor
  • Vaginal Birth after Cesarean* / adverse effects
  • Vaginal Birth after Cesarean* / methods
  • Vaginal Birth after Cesarean* / statistics & numerical data