COVID-19-Associated Histoplasmosis in an AIDS Patient

Rossana Patricia Basso; Vanice Rodrigues Poester; Jéssica Louise Benelli; David A Stevens; Heruza Einsfeld Zogbi; Izadora Clezar da S Vasconcellos; Alessandro Comarú Pasqualotto; Melissa Orzechowski Xavier

doi:10.1007/s11046-020-00505-1

COVID-19-Associated Histoplasmosis in an AIDS Patient

Mycopathologia. 2021 Mar;186(1):109-112. doi: 10.1007/s11046-020-00505-1. Epub 2020 Nov 6.

Affiliations

¹ Pós-Graduação em Ciências da Saúde, Laboratório de Micologia, Faculdade de Medicina, Universidade Federal do Rio Grande (FAMED-FURG), Campus Saúde, Visconde de Paranaguá 102, Centro, Rio Grande, RS, 96201-900, Brazil.
² Hospital Universitário Dr. Miguel Riet Corrêa Jr. (HU-FURG), vinculado à Empresa Brasileira de Serviços Hospitalares (EBSERH), Rio Grande, RS, Brazil.
³ California Institute for Medical Research, San Jose, CA, USA.
⁴ Division of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA.
⁵ Programa de Pós-Graduação em Patologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
⁶ Pós-Graduação em Ciências da Saúde, Laboratório de Micologia, Faculdade de Medicina, Universidade Federal do Rio Grande (FAMED-FURG), Campus Saúde, Visconde de Paranaguá 102, Centro, Rio Grande, RS, 96201-900, Brazil. [email protected].
⁷ California Institute for Medical Research, San Jose, CA, USA. [email protected].
⁸ Division of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA. [email protected].

Abstract

Most reports associating fungal infections with COVID-19 have been cases of invasive aspergillosis. Here, we report a case of severe histoplasmosis and COVID-19 infections in an HIV patient in Rio Grande, Southern Brazil. Histoplasmosis must be included as a diagnostic possibility in opportunistic fungal co-infections in COVID-19 patients with AIDS, mainly in endemic areas.

Keywords: AIDS; COVID-19; Histoplasma capsulatum; Mycoses; SARS-CoV-2.

Publication types

Case Reports

MeSH terms

AIDS-Related Opportunistic Infections / diagnosis
AIDS-Related Opportunistic Infections / drug therapy*
AIDS-Related Opportunistic Infections / etiology*
Acquired Immunodeficiency Syndrome / complications*
Acquired Immunodeficiency Syndrome / drug therapy
Adult
Antifungal Agents / therapeutic use*
Brazil
COVID-19 / complications*
COVID-19 / microbiology
Coinfection
Female
Histoplasmosis / diagnosis*
Histoplasmosis / drug therapy
Histoplasmosis / etiology*
Humans
SARS-CoV-2
Treatment Outcome

Substances

Antifungal Agents