First-in-children epicardial mapping of the heart: unravelling arrhythmogenesis in congenital heart disease

Interact Cardiovasc Thorac Surg. 2021 Jan 1;32(1):137-140. doi: 10.1093/icvts/ivaa233.

Abstract

Patients with congenital heart disease (CHD) are prone to develop atrial and ventricular arrhythmias. Multiple factors throughout life contribute to arrhythmogenicity substrate such as (i) (longstanding) volume and/or pressure overload, (ii) scar tissue, (iii) ageing-related structural remodelling, (iv) cardiovascular risk factors and (v) tachycardia-induced remodelling. At present, it is unknown whether, and to what extent, paediatric patients with CHD have atrial or ventricular conduction disorders early in life and whether there is a correlation between duration of volume/pressure overload and extensiveness of conduction disorders. To investigate this, we initiated high-resolution intraoperative epicardial mapping in paediatric patients with CHD undergoing primary open-heart surgery.

Keywords: Cardiac atrial mapping; Congenital heart disease; Electrophysiology.

MeSH terms

  • Arrhythmias, Cardiac / diagnosis*
  • Arrhythmias, Cardiac / etiology
  • Child
  • Electrodes
  • Epicardial Mapping*
  • Female
  • Heart Atria / diagnostic imaging
  • Heart Atria / physiopathology
  • Heart Defects, Congenital / diagnosis*
  • Heart Defects, Congenital / surgery
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology
  • Humans
  • Infant
  • Male