Multidrug-resistant Acinetobacter baumannii outbreaks: a global problem in healthcare settings

Rev Soc Bras Med Trop. 2020 Nov 6:53:e20200248. doi: 10.1590/0037-8682-0248-2020. eCollection 2020.

Abstract

Introduction: The increase in the prevalence of multidrug-resistant Acinetobacter baumannii infections in hospital settings has rapidly emerged worldwide as a serious health problem.

Methods: This review synthetizes the epidemiology of multidrug-resistant A. baumannii, highlighting resistance mechanisms.

Conclusions: Understanding the genetic mechanisms of resistance as well as the associated risk factors is critical to develop and implement adequate measures to control and prevent acquisition of nosocomial infections, especially in an intensive care unit setting.

Publication types

  • Review

MeSH terms

  • Acinetobacter Infections* / drug therapy
  • Acinetobacter Infections* / epidemiology
  • Acinetobacter baumannii*
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Cross Infection* / drug therapy
  • Cross Infection* / epidemiology
  • Delivery of Health Care
  • Disease Outbreaks
  • Drug Resistance, Multiple, Bacterial
  • Humans

Substances

  • Anti-Bacterial Agents