Treatment-Induced Neuropathy of Diabetes in Youth: Case Series of a Heterogeneous and Challenging Complication

Eirene G Alexandrou; Sarah D Corathers; Amit Lahoti; Jacob Redel; Siobhan Tellez; Nana-Hawa Yayah Jones; Ahlee Kim

doi:10.1210/jendso/bvaa154

Treatment-Induced Neuropathy of Diabetes in Youth: Case Series of a Heterogeneous and Challenging Complication

J Endocr Soc. 2020 Oct 15;4(12):bvaa154. doi: 10.1210/jendso/bvaa154. eCollection 2020 Dec 1.

Authors

Eirene G Alexandrou^{1

2}, Sarah D Corathers^{3

4}, Amit Lahoti^{5

6}, Jacob Redel^{7

8}, Siobhan Tellez³, Nana-Hawa Yayah Jones^{3

4}, Ahlee Kim^{5

6}

Affiliations

¹ Division of Endocrinology, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa.
² Department of Pediatrics, University of Iowa, Iowa City, Iowa.
³ Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
⁴ Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio.
⁵ Division of Endocrinology, Le Bonheur Children's Hospital, Memphis, Tennessee.
⁶ Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee.
⁷ Division of Endocrinology, Children's Mercy Hospital, Kansas City, Missouri.
⁸ Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.

Abstract

Treatment-induced neuropathy of diabetes (TIND) is a small fiber neuropathy precipitated by rapid correction of hyperglycemia. Literature on TIND in pediatric diabetes is scarce. We present 7 cases of TIND in children and young adults, increasing awareness of this condition in pediatric diabetes and broadening the scope of published knowledge.

Keywords: diabetes complications; diabetic neuropathy; pain; pediatric diabetes; somatic pain.

Publication types

Case Reports