Abstract
Renal capsule transplantation is a very helpful method to grow embryonic tissues or tumors in a vascular environment, allowing for long-term engraftment and biological analyses. This chapter describes the surgical procedure for the transplantation of embryonic skeletal elements in the renal capsule of adult mice and points out the manipulations that can be applied for assaying the role of angiogenesis during bone development and repair.
Keywords:
Angiogenesis; Renal capsule transplantation; Skeletal development; Skeletal repair.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adventitia / growth & development
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Adventitia / pathology
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Animals
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Bone Development / genetics*
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Epithelium / growth & development
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Epithelium / pathology
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Humans
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Kidney / growth & development
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Kidney / pathology
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Kidney Transplantation / methods*
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Lymphangiogenesis / genetics
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Lymphatic Vessels / cytology
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Mice
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Morphogenesis / genetics*
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Neovascularization, Pathologic / genetics
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Neovascularization, Physiologic / genetics*
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Organogenesis / genetics