Prevalence of impaired physiological function consistent with Relative Energy Deficiency in Sport (RED-S): an Australian elite and pre-elite cohort

Br J Sports Med. 2021 Jan;55(1):38-45. doi: 10.1136/bjsports-2019-101517. Epub 2020 Nov 16.

Abstract

Objectives: Athlete health, training continuity and performance can be impeded as a result of Relative Energy Deficiency in Sport (RED-S). Here we report the point prevalence of symptoms described by the RED-S model in a mixed-sport cohort of Australian female athletes.

Methods: Elite and pre-elite female athletes (n=112) from eight sports completed validated questionnaires and underwent clinical assessment to assess the point prevalence of RED-S symptoms. Questionnaires included the Depression, Anxiety and Stress Questionnaire (DASS-21), Generalized Anxiety Disorder (GAD-7), Center for Epidemiological Studies Depression Scale (CES-D), SCOFF questionnaire for disordered eating, Low Energy Availability in Females Questionnaire (LEAF-Q), and a custom questionnaire on injury and illness. Clinical assessment comprised resting metabolic rate (RMR) assessment, dual-energy X-ray absorptiometry-derived body composition and bone mineral density, venous and capillary blood samples, and the Mini International Neuropsychiatric Interview (MINI 7.0.2). Descriptive prevalence statistics are presented.

Results: Almost all (80%) participants (age 19 (range 15-32) years; mass 69.5±10.3 kg; body fat 23.1%±5.0%) demonstrated at least one symptom consistent with RED-S, with 37% exhibiting between two and three symptoms. One participant demonstrated five symptoms. Impaired function of the immunological (28%, n=27), haematological (31%, n=33) and gastrointestinal (47%, n=51) systems were most prevalent. A moderate to high (11%-55%) prevalence of risk of low energy availability was identified via RMR and LEAF-Q, and identified mental illnesses were prevalent in one-third of the assessed cohort.

Conclusion: Symptoms described by the RED-S model were prevalent in this cohort, supporting the need for improved awareness, monitoring and management of these symptoms in this population.

Keywords: athlete; female; health; relative energy deficiency.

Publication types

  • Observational Study

MeSH terms

  • Absorptiometry, Photon
  • Adolescent
  • Adult
  • Australia / epidemiology
  • Basal Metabolism
  • Biomarkers / blood
  • Cardiorespiratory Fitness
  • Competitive Behavior / physiology*
  • Cross-Sectional Studies
  • Female
  • Health Surveys
  • Humans
  • Interview, Psychological
  • Leptin / blood
  • Mental Disorders / diagnosis
  • Mental Disorders / epidemiology
  • Prevalence
  • Relative Energy Deficiency in Sport / diagnosis
  • Relative Energy Deficiency in Sport / epidemiology*
  • Relative Energy Deficiency in Sport / psychology
  • Risk Factors
  • Young Adult

Substances

  • Biomarkers
  • Leptin