Hepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques

H Richard Alexander Jr; Virginia Devi-Chou

doi:10.1016/j.soc.2020.08.007

Hepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques

Surg Oncol Clin N Am. 2021 Jan;30(1):175-188. doi: 10.1016/j.soc.2020.08.007. Epub 2020 Oct 20.

Authors

H Richard Alexander Jr¹, Virginia Devi-Chou²

Affiliations

¹ Department of Surgery, Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 195 Little Albany Street, Room 2009, New Brunswick, NJ 08901, USA. Electronic address: [email protected].
² Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

PMID: 33220804
DOI: 10.1016/j.soc.2020.08.007

Abstract

The management of patients with diffuse liver metastases remains a significant clinical challenge. In many cancer patients, metastatic disease may be isolated to the liver or the liver may be the dominant site of progressive metastatic cancer. In this setting, progression of disease in the liver generally is the most significant cause of morbidity and mortality.

Keywords: Diffuse liver; Hepatic perfusion; IHP; Liver metastases; Metachronous disease; Metastatic cancer; PHP.

Publication types

Review

MeSH terms

Chemotherapy, Cancer, Regional Perfusion*
Humans
Liver Neoplasms* / drug therapy
Melphalan / therapeutic use
Perfusion

Substances

Melphalan