SPLEnic salvage and complications after splenic artery EmbolizatioN for blunt abdomINal trauma: the SPLEEN-IN study

Warren Clements; Tim Joseph; Jim Koukounaras; Gerard S Goh; Heather K Moriarty; Joseph Mathew; Tuan D Phan

doi:10.1186/s42155-020-00185-4

SPLEnic salvage and complications after splenic artery EmbolizatioN for blunt abdomINal trauma: the SPLEEN-IN study

CVIR Endovasc. 2020 Dec 7;3(1):92. doi: 10.1186/s42155-020-00185-4.

Authors

Warren Clements^{1

2

3}, Tim Joseph⁴, Jim Koukounaras^{4

5}, Gerard S Goh^{4

5

6}, Heather K Moriarty^{4

5}, Joseph Mathew^{6

7}, Tuan D Phan⁴

Affiliations

¹ Department of Radiology, Alfred Health, 55 Commercial Road, Melbourne, VIC, 3004, Australia. [email protected].
² Department of Surgery, Monash University, Melbourne, Australia. [email protected].
³ National Trauma Research Institute, Central Clinical School, Monash University, Melbourne, Australia. [email protected].
⁴ Department of Radiology, Alfred Health, 55 Commercial Road, Melbourne, VIC, 3004, Australia.
⁵ Department of Surgery, Monash University, Melbourne, Australia.
⁶ National Trauma Research Institute, Central Clinical School, Monash University, Melbourne, Australia.
⁷ Department of Trauma, Alfred Health, Melbourne, Victoria, Australia.

Abstract

Background: As an adjunct to non-operative management, splenic artery embolization (SAE) has been increasingly utilized throughout the world and is now the standard of care for hemodynamically stable patients. This study aimed to retrospectively assess the rate of splenic salvage and complications after SAE for blunt trauma at a level 1 trauma center using the 2018 update to the AAST criteria, and further sub-stratify the role of angiography in AAST grade III injuries with significant hemoperitoneum. All patients between 1 January 2009 and 1 January 2019 who underwent blunt trauma and proceeded to embolization were included. Data was collected concerning initial injury grade, location of embolization, type of embolic material used, complications, and need for subsequent splenectomy. Technical success was defined as successful angiographic occlusion of the target artery at the conclusion of embolization. Clinical success was defined as splenic salvage at discharge. Vascular lesions were characterized including those with active bleeding, pseudoaneurysm, and arterio-venous fistula.

Results: Two hundred thirty-two patients were included in the study. Treatments were performed at a median of 0 days (range 0-28 days) and the median AAST grade was IV (range III-V). Technical success was achieved in all patients. There were 13 complications (5.6%) consisting of re-bleed (9, 3.9%), infarction (3, 1.3%), and access site haematoma (1, 0.43%). Clinical success was achieved in 97% of patients with 7 patients requiring splenectomy after SAE (3.0%) at a median time of 4 days (range 0-17 days). Angiography in patients with grade III injuries identified 18 occult vascular injuries not identified at initial CT (p < 0.0001).

Conclusions: The SPLEEN-IN study shows that treatment of intermediate-high grade blunt force traumatic splenic injuries using SAE resulted in a low rate of complication and splenic salvage in 97% of patients, providing a safe and effective treatment in stable patients. In addition, angiography of grade III injuries identified occult vascular lesions and may warrant treatment of select patients in this cohort.

Level of evidence: Level 3.

Keywords: Embolization; Hemorrhage; SAE; Spleen; Trauma.