A Case of Adenomyoepithelioma With a Pleomorphic Adenoma-Like Component of the Male Breast

Int J Surg Pathol. 2021 Aug;29(5):538-542. doi: 10.1177/1066896920978824. Epub 2020 Dec 8.

Abstract

Adenomyoepithelioma (AME) of the male breast is a rare tumor characterized by biphasic proliferation of gland epithelial cells and myoepithelial cells. Though pleomorphic adenoma (PA) is also known to be an epithelial-myoepithelial tumor in the breast, and these tumors are considered to exist on the same spectrum by some authors, to the best of our knowledge, there have been no reports of a clear transition from AME to PA in the male breast. Therefore, the case of an 85-year-old man with AME with PA-like components is presented.

Keywords: adenomyoepithelioma; biphasic tumor; epithelial-myoepithelial tumor; male breast; pleomorphic adenoma.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Pleomorphic / diagnosis*
  • Adenoma, Pleomorphic / pathology
  • Adenoma, Pleomorphic / surgery
  • Adenomyoepithelioma / diagnosis*
  • Adenomyoepithelioma / pathology
  • Adenomyoepithelioma / surgery
  • Aged, 80 and over
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Breast Neoplasms, Male / diagnosis*
  • Breast Neoplasms, Male / pathology
  • Breast Neoplasms, Male / surgery
  • Humans
  • Male
  • Mammary Glands, Human / pathology*
  • Mammary Glands, Human / surgery

Substances

  • Biomarkers, Tumor