The renin-angiotensin-aldosterone system inhibitors in COVID-19: from acidosis to ventilation and immunity

Swiss Med Wkly. 2020 Dec 11:150:w20444. doi: 10.4414/smw.2020.20444. eCollection 2020 Nov 30.

Authors

Wan-Hui Liao¹, Gee-Gwo Yang², Maciej Henneberg³

Affiliations

¹ Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan, R. O. C. / Department of Medical Education, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan, R. O. C.
² Department of Medical Education, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan, R. O. C. / Division of Chest Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, R. O. C.
³ Institute of Evolutionary Medicine, University of Zurich, Switzerland / Biological Anthropology and Comparative Anatomy Unit, University of Adelaide, Australia.

PMID: 33306813
DOI: 10.4414/smw.2020.20444

No abstract available

MeSH terms

Acid-Base Equilibrium
Acidosis / chemically induced
Acidosis / immunology*
Acidosis / metabolism
Angiotensin Receptor Antagonists / adverse effects*
Angiotensin Receptor Antagonists / therapeutic use
Angiotensin-Converting Enzyme 2 / metabolism
Angiotensin-Converting Enzyme Inhibitors / adverse effects*
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
CD4-Positive T-Lymphocytes / immunology
COVID-19 / immunology*
COVID-19 / metabolism
Cytokine Release Syndrome / immunology
Glucocorticoids / immunology
Glucocorticoids / metabolism
Histocompatibility Antigens Class I / immunology
Humans
Hypertension / drug therapy
Immunity, Cellular / immunology*
Killer Cells, Natural / immunology
Natural Killer T-Cells / immunology
Pulmonary Ventilation*
Renal Elimination
Renin-Angiotensin System / immunology*
Renin-Angiotensin System / physiology
SARS-CoV-2 / metabolism
T-Lymphocytes, Cytotoxic / immunology

Substances

Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Glucocorticoids
Histocompatibility Antigens Class I
Angiotensin-Converting Enzyme 2