Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease

Cancer. 1988 Jan 15;61(2):252-4. doi: 10.1002/1097-0142(19880115)61:2<252::aid-cncr2820610209>3.0.co;2-g.

Abstract

Two patients developed breast cancer after treatment of Hodgkin's disease. Both had received mediastinal irradiation 13 to 15 years, respectively, before the diagnosis of breast carcinoma. One patient had synchronous bilateral breast cancer when the diagnosis was made. Discussed is the risk of mammary carcinoma as a second malignant neoplasm in patients treated for Hodgkin's disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols*
  • Breast Neoplasms / etiology*
  • Carcinoma / etiology*
  • Female
  • Hodgkin Disease / drug therapy
  • Hodgkin Disease / radiotherapy*
  • Humans
  • Mechlorethamine / administration & dosage
  • Neoplasms, Radiation-Induced / etiology*
  • Prednisone / administration & dosage
  • Procarbazine / administration & dosage
  • Vincristine / administration & dosage

Substances

  • Procarbazine
  • Mechlorethamine
  • Vincristine
  • Prednisone

Supplementary concepts

  • MOPP protocol