Effects of deltamethrin subacute exposure in snakehead fish, Channa argus: Biochemicals, antioxidants and immune responses

Yidi Kong; Min Li; Xiaofeng Shan; Guiqin Wang; Guanghong Han

doi:10.1016/j.ecoenv.2020.111821

Effects of deltamethrin subacute exposure in snakehead fish, Channa argus: Biochemicals, antioxidants and immune responses

Ecotoxicol Environ Saf. 2021 Feb:209:111821. doi: 10.1016/j.ecoenv.2020.111821. Epub 2020 Dec 24.

Authors

Yidi Kong¹, Min Li¹, Xiaofeng Shan², Guiqin Wang³, Guanghong Han⁴

Affiliations

¹ College of Animal Science and Technology, Jilin Agriculture University, Changchun 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agriculture University, Changchun 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun 130118, China.
² College of Animal Science and Technology, Jilin Agriculture University, Changchun 130118, China.
³ College of Animal Science and Technology, Jilin Agriculture University, Changchun 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agriculture University, Changchun 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun 130118, China. Electronic address: [email protected].
⁴ Department of Oral Geriatrics, Hospital of Stomatology, Jilin University, Changchun 130021, China. Electronic address: [email protected].

PMID: 33360593
DOI: 10.1016/j.ecoenv.2020.111821

Abstract

To evaluate the effects on biochemicals, antioxidants, immune responses and disease resistance of the snakehead fish, following exposure to deltamethrin at 0.061, 0.121, 0.242, 0.485 and 0.970 μg/L. After 28 d, the biochemical, the levels of antioxidant enzymes and immune enzymes in liver, spleen, kidney and intestine were negatively related to the concentrations of deltamethrin exposure. Likewise, the survival rates of the fish after 7 d challenge with Aeromonas veronii were negatively related. The levels of IL-1β, IL-8, TNF-α, Hsp70 and malondialdehyde in liver, spleen, kidney and intestine were positively connected to the concentrations of deltamethrin exposure. Results demonstrated that environmentally relevant concentrations (0.121, 0.242, 0.485 and 0.970 μg/L) inhibited the biochemicals, antioxidants and immune responses and disease resistance of snakehead fish.

Keywords: Antioxidant capacity; Channa argus; Deltamethrin; Disease resistance; Immune responses.

MeSH terms

Animals
Antioxidants / metabolism
Fishes / immunology
Fishes / physiology*
Immunity
Insecticides / toxicity*
Kidney
Liver / drug effects
Malondialdehyde / metabolism
Nitriles / toxicity*
Pyrethrins / toxicity*
Spleen / drug effects

Substances

Antioxidants
Insecticides
Nitriles
Pyrethrins
decamethrin
Malondialdehyde