Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness

Karan Seegobin; Muhamad Alhaj Moustafa; Deborah Fischer; Katelyn Keller; Jacquelyn Hastings; Mohamed A Kharfan-Dabaja; Ernesto Ayala; Vivek Gupta; Han W Tun; Liuyan Jiang

doi:10.1002/ccr3.3231

Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness

Clin Case Rep. 2020 Aug 14;8(12):2629-2633. doi: 10.1002/ccr3.3231. eCollection 2020 Dec.

Affiliations

¹ Division of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida.
² Department of Radiology Mayo Clinic Jacksonville Florida.
³ Department of Pathology Mayo Clinic Jacksonville Florida.

Abstract

ALK-positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instituted in patients with CNS involvement or those at increased CNS risk.

Keywords: ALK+ anaplastic large cell lymphoma; neurolymphomatosis; optic nerves.

Publication types

Case Reports