Acrocyanosis and digital necrosis are associated with poor prognosis in COVID-19

Guitti Pourdowlat; Zohre Naderi; Farhad Seif; Davood Mansouri; Hanieh Raji

doi:10.1002/ccr3.3276

Acrocyanosis and digital necrosis are associated with poor prognosis in COVID-19

Clin Case Rep. 2020 Aug 30;8(12):2769-2772. doi: 10.1002/ccr3.3276. eCollection 2020 Dec.

Authors

Guitti Pourdowlat¹, Zohre Naderi², Farhad Seif^{3

4}, Davood Mansouri^{5

6

7}, Hanieh Raji⁸

Affiliations

¹ Chronic Respiratory Diseases Research Center National Research Institute of Tuberculosis and Lung Diseases Shahid Beheshti University of Medical Sciences Tehran Iran.
² Department of Pulmonology Isfahan University of Medical Sciences Isfahan Iran.
³ Department of Immunology and Allergy Academic Center for Education, Culture, and Research Tehran Iran.
⁴ Neuroscience Research Center Iran University of Medical Sciences Tehran Iran.
⁵ Department of Clinical Immunology and Infectious Diseases National Research Institute of Tuberculosis and Lung Diseases Shahid Beheshti University of Medical Sciences Tehran Iran.
⁶ The Clinical Tuberculosis and Epidemiology Research Center National Research Institute of Tuberculosis and Lung Diseases Shahid Beheshti University of Medical Sciences Tehran Iran.
⁷ Pediatric Respiratory Diseases Research Center National Research Institute of Tuberculosis and Lung Diseases Shahid Beheshti University of Medical Sciences Tehran Iran.
⁸ Department of Internal Medicine Air pollution and Respiratory Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.

Abstract

Acrocyanosis and digital necrosis, which caused by microangiopathic and immunothrombosis phenomenon, may accompanied by microvascular involvement of other organs. Therefore, this finding can play a prognostic role in covid-19 outcome.

Keywords: COVID‐19; acrocyanosis; digital necrosis; interleukin‐6; noradrenaline.

Publication types

Case Reports