Atypical cellular neurothekeoma (ACN) of the elderly: case report and brief review of the literature

Pathologica. 2020 Dec;112(4):210-213. doi: 10.32074/1591-951X-104.

Abstract

Atypical cellular neurothekeoma (ACN) is an aggressive and rare variant of cellular neurothekeoma. Only few cases have been reported in the literature and the biological behavior seems to be uncertain. We describe the case of an ACN presenting on the scalp of an elderly man, emphasizing the cytologic features of malignancy. In addition, we provide a brief overview of the literature and discuss the differential diagnosis with other entities, and the possible diagnostic pitfalls.

Keywords: atypical cellular neurothekeoma; diagnostic pitfalls; scalp elderly.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • Male
  • Neurothekeoma* / diagnosis
  • Neurothekeoma* / pathology
  • Scalp / pathology*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology
  • Soft Tissue Neoplasms / diagnosis
  • Soft Tissue Neoplasms / pathology

Substances

  • Biomarkers, Tumor