Non-small-cell lung cancer infiltrated with chronic myelomonocytic leukaemia: a molecular diagnostic challenge to recognise mixed cancers in a single biopsy

Histopathology. 2021 Jun;78(7):1043-1046. doi: 10.1111/his.14326. Epub 2021 Apr 3.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Amino Acid Substitution
  • Antineoplastic Agents / therapeutic use*
  • Biopsy
  • Carcinoma, Non-Small-Cell Lung / diagnostic imaging*
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Class I Phosphatidylinositol 3-Kinases / genetics*
  • Crizotinib / therapeutic use
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Leukemia, Myelomonocytic, Chronic / diagnostic imaging*
  • Leukemia, Myelomonocytic, Chronic / drug therapy
  • Leukemia, Myelomonocytic, Chronic / genetics
  • Leukemia, Myelomonocytic, Chronic / pathology
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology
  • Lymphocytes, Tumor-Infiltrating
  • Male
  • Mutation
  • Pathology, Molecular
  • Proto-Oncogene Proteins c-met / genetics*
  • Sequence Analysis, DNA
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents
  • Crizotinib
  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • Class I Phosphatidylinositol 3-Kinases
  • PIK3CA protein, human
  • MET protein, human
  • Proto-Oncogene Proteins c-met