Efferent unmasking of speech-in-noise encoding?

Int J Audiol. 2021 Sep;60(9):677-686. doi: 10.1080/14992027.2020.1862425. Epub 2021 Jan 10.

Abstract

Objective: The medial olivocochlear (MOC) reflex provides efferent feedback from the brainstem to cochlear outer hair cells. Physiologic studies have demonstrated that the MOC reflex is involved in "unmasking" of signals-in-noise at the level of the auditory nerve; however, its functional importance in human hearing remains unclear.

Design: This study examined relationships between pre-neural measurements of MOC reflex strength (click-evoked otoacoustic emission inhibition; CEOAE) and neural measurements of speech-in-noise encoding (speech frequency following response; sFFR) in four conditions (Quiet, Contralateral Noise, Ipsilateral Noise, and Ipsilateral + Contralateral Noise). Three measures of CEOAE inhibition (amplitude reduction, effective attenuation, and input-output slope inhibition) were used to quantify pre-neural MOC reflex strength. Correlations between pre-neural MOC reflex strength and sFFR "unmasking" (i.e. response recovery from masking effects with activation of the MOC reflex in time and frequency domains) were assessed.

Study sample: 18 young adults with normal hearing.

Results: sFFR unmasking effects were insignificant, and there were no correlations between pre-neural MOC reflex strength and sFFR unmasking in the time or frequency domain.

Conclusion: Our results do not support the hypothesis that the MOC reflex is involved in speech-in-noise neural encoding, at least for features that are represented in the sFFR at the SNR tested.

Keywords: Efferent; frequency following response; medial olivocochlear reflex; otoacoustic emissions.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acoustic Stimulation
  • Cochlea*
  • Efferent Pathways
  • Humans
  • Noise / adverse effects
  • Olivary Nucleus*
  • Otoacoustic Emissions, Spontaneous
  • Speech