Small-intestinal factors promote encystation of Giardia lamblia in vitro

Infect Immun. 1988 Mar;56(3):705-7. doi: 10.1128/iai.56.3.705-707.1988.

Abstract

Bile salts and fatty acids stimulated differentiation of cultured Giardia lamblia trophozoites into water-resistant cysts at the slightly alkaline pH of the small intestinal lumen. Maximum encystation occurred at pH 7.8. Thus, specific small-intestinal factors may influence encystation in vivo as well as in vitro.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Bile Acids and Salts / physiology
  • Fatty Acids / physiology
  • Giardia / cytology*
  • Hydrogen-Ion Concentration
  • In Vitro Techniques
  • Intestine, Small / parasitology*

Substances

  • Bile Acids and Salts
  • Fatty Acids