Neurologic complications of lung cancer

Cancer. 2020 Oct 15;126(20):4455-4465. doi: 10.1002/cncr.32772. Epub 2020 Jul 30.

Abstract

Lung cancer and its associated treatments can cause various neurologic complications, including brain and leptomeningeal metastases, epidural spinal cord compression, cerebrovascular events, and treatment-related neurotoxicities. Lung cancer care has significantly changed in the last 5 to 10 years, with novel therapies that have affected aspects of neurologic complication management. Herein, the authors review the potential neurologic complications of lung cancer, including important clinical and therapeutic aspects of care.

Keywords: brain metastases; epidural spinal cord compression; leptomeningeal; lung cancer.

Publication types

  • Review

MeSH terms

  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / pathology
  • Nervous System Diseases / etiology*
  • Nervous System Diseases / pathology