Clinical Characteristics and Outcomes of Patients with COVID-19 Infection: The Results of the SARS-RAS Study of the Italian Society of Hypertension

High Blood Press Cardiovasc Prev. 2021 Jan;28(1):5-11. doi: 10.1007/s40292-020-00429-3. Epub 2021 Jan 20.

Abstract

The COVID-19 infection has rapidly spread around the world and a second wave is sweeping in many countries. Different clinical and epidemiological aspects characterize the disease and their understanding is necessary to better face the management of the pandemic in progress. The Italian society of arterial hypertension with the SARS-RAS study has contributed significantly to the knowledge of the interaction between inhibition of the renin-angiotensin system and COVID-19 infection. Furthermore, the study results help to understand some of the main aspects related to mortality and morbidity deriving from the infection through a multicentre analysis throughout the national territory.

Keywords: Anti-hypertensive therapy; Comorbidities; Frailty; Sars-Cov2; Sex-differences.

Publication types

  • Multicenter Study
  • Observational Study
  • Practice Guideline

MeSH terms

  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / therapeutic use*
  • Arterial Pressure / drug effects*
  • COVID-19 / diagnosis
  • COVID-19 / mortality
  • COVID-19 / therapy*
  • Comorbidity
  • Cross-Sectional Studies
  • Frailty / mortality
  • Humans
  • Hypertension / diagnosis
  • Hypertension / drug therapy*
  • Hypertension / mortality
  • Hypertension / physiopathology
  • Italy / epidemiology
  • Renin-Angiotensin System / drug effects*
  • Risk Assessment
  • Risk Factors
  • Severity of Illness Index
  • Sex Factors
  • Treatment Outcome

Substances

  • Antihypertensive Agents