Strategies for Treating Inherited Retinal Degeneration With Large Genes That Are Not Amenable to Adeno-Associated Virus-Based Gene Replacement Therapy

JAMA Ophthalmol. 2021 Mar 1;139(3):328-329. doi: 10.1001/jamaophthalmol.2020.6427.

Authors

Paul Yang^{1

2}, Mark E Pennesi^{1

2

3}, Richard G Weleber^{1

2

3}

Affiliations

¹ Casey Eye Institute, Oregon Health and Science University, Portland.
² Department of Ophthalmology, Oregon Health and Science University, Portland.
³ Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland.

PMID: 33507212
DOI: 10.1001/jamaophthalmol.2020.6427

No abstract available

Publication types

Comment

MeSH terms

Clustered Regularly Interspaced Short Palindromic Repeats
Dependovirus* / genetics
Genetic Therapy
Genetic Vectors
Humans
Retinal Degeneration* / genetics
Retinal Degeneration* / therapy

Grants and funding

K08 EY026650/EY/NEI NIH HHS/United States