RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression

Cancer Cell. 2021 Mar 8;39(3):294-296. doi: 10.1016/j.ccell.2021.01.008. Epub 2021 Jan 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Disease Progression
  • Humans
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / pathology
  • Mutation / genetics*
  • Phosphorylation / genetics
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins c-raf / genetics*
  • Proto-Oncogene Proteins p21(ras) / genetics*
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • KRAS protein, human
  • Proto-Oncogene Proteins
  • TP53 protein, human
  • Tumor Suppressor Protein p53
  • Proto-Oncogene Proteins c-raf
  • Raf1 protein, human
  • Proto-Oncogene Proteins p21(ras)