Effects of magnolol on egg production, egg quality, antioxidant capacity, and intestinal health of laying hens in the late phase of the laying cycle

Poult Sci. 2021 Feb;100(2):835-843. doi: 10.1016/j.psj.2020.10.047. Epub 2020 Nov 2.

Abstract

Magnolol is a multifunctional plant polyphenol. To evaluate the effects of magnolol on laying hens in the late laying period, 360 (50-week-old) laying hens were randomly assigned to 4 dietary treatments: a non-supplemented control diet (C), and control diets supplemented with 100, 200, and 300 mg/kg of magnolol (M100, M200, and M300), respectively. Each treatment had 6 replicates with 15 hens per replicate. Results showed that dietary supplementation of 200 and 300 mg/kg of magnolol increased the laying rate and the M200 group had a lower feed conversion ratio (P < 0.05). Magnolol supplementation (200 and 300 mg/kg) could linearly increase albumen height and Haugh unit of fresh eggs in the late phase of the laying cycle (P < 0.01). And magnolol linearly alleviated the decline of the albumen height and Haugh unit of eggs stored for 14 d (P < 0.01). The total superoxide dismutase activity in the ovaries of M100 group was greater than that in the other treatments (P < 0.05). As dietary magnolol levels increased, villus height of jejunum and ileum linearly increased (P < 0.01). M200 and M300 groups had higher expression level of occludin in the ileum compared with group C (P < 0.01). The level of nitric oxide production and inducible nitric oxide synthase expression in the ileum of M200 group were lower than that in the C group (P < 0.05). In conclusion, dietary supplementation of 200 and 300 mg/kg magnolol can improve hen performance, albumen quality of fresh and storage eggs, and hepatic lipid metabolism in the late laying cycle. Also, magnolol has a good effect on increasing villi and improving the intestinal mucosal mechanical barrier function.

Keywords: antioxidant capacity; egg quality; hen; intestinal health; magnolol.

Publication types

  • Randomized Controlled Trial, Veterinary

MeSH terms

  • Animal Feed / analysis
  • Animals
  • Antioxidants / administration & dosage
  • Antioxidants / pharmacology*
  • Biphenyl Compounds / administration & dosage
  • Biphenyl Compounds / pharmacology*
  • Chickens / metabolism
  • Chickens / physiology*
  • Diet / veterinary
  • Dietary Supplements
  • Eggs / standards*
  • Female
  • Intestines / anatomy & histology
  • Intestines / drug effects*
  • Intestines / physiology
  • Lignans / administration & dosage
  • Lignans / pharmacology*
  • Lipid Metabolism / drug effects
  • Liver / drug effects
  • Liver / metabolism
  • Oviposition / drug effects*
  • Ovum

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Lignans
  • magnolol