Chronic dapsone use causing methemoglobinemia with oxidative hemolysis and dyserythropoiesis

Am J Hematol. 2021 Dec 1;96(12):1715-1716. doi: 10.1002/ajh.26116. Epub 2021 Feb 15.

Authors

Christian Aledia Gallardo¹, Bingwen Eugene Fan^{1

2

3

4

5}, Kian Guan Eric Lim², Ponnudurai Kuperan^{1

2

3

4

5}

Affiliations

¹ Department of Haematology, Tan Tock Seng Hospital, Singapore.
² Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore.
³ Department of Laboratory Medicine, Khoo Teck Puat Hospital, Singapore.
⁴ Lee Kong Chian School of Medicine, Singapore.
⁵ Yong Loo Lin School of Medicine, Singapore.

PMID: 33524190
DOI: 10.1002/ajh.26116

No abstract available

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Anti-Infective Agents / adverse effects*
Dapsone / adverse effects*
Erythrocytes / drug effects
Erythrocytes / pathology
Erythropoiesis / drug effects*
Female
Folic Acid Antagonists / adverse effects
Hemolysis / drug effects*
Humans
Methemoglobinemia / chemically induced*
Methemoglobinemia / pathology
Oxidative Stress / drug effects

Substances

Anti-Infective Agents
Folic Acid Antagonists
Dapsone