Ureaplasma septic polyarthritis in a young woman with neuromyelitis optica receiving rituximab

Rachel Harold; Gary L Simon; Hana Akselrod; Marc O Siegel; Afsoon Roberts

doi:10.1136/bcr-2020-237916

Ureaplasma septic polyarthritis in a young woman with neuromyelitis optica receiving rituximab

BMJ Case Rep. 2021 Feb 1;14(2):e237916. doi: 10.1136/bcr-2020-237916.

Authors

Rachel Harold¹, Gary L Simon², Hana Akselrod², Marc O Siegel², Afsoon Roberts²

Affiliations

¹ Infectious Diseases, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA [email protected].
² Infectious Diseases, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Abstract

We report a case of septic polyarthritis caused by Ureaplasma urealyticum in a woman with neuromyelitis optica who was receiving rituximab. Her case exemplifies some of the unique characteristics of invasive Ureaplasma infections that can lead to delayed diagnosis as well as treatment challenges including recurrence following antibiotic discontinuation.

Keywords: bone and joint infections; immunological products and vaccines; sexual transmitted infections (bacterial).

Publication types

Case Reports

MeSH terms

Arthritis, Infectious / diagnosis
Arthritis, Infectious / immunology
Arthritis, Infectious / microbiology*
Arthritis, Infectious / therapy
Arthroscopy
Diagnostic Errors
Doxycycline / therapeutic use
Female
Gonorrhea / diagnosis
Gonorrhea / drug therapy
Humans
Immunocompromised Host*
Immunologic Factors / adverse effects*
Knee Joint / surgery
Magnetic Resonance Imaging
Neuromyelitis Optica / drug therapy*
Nucleic Acid Amplification Techniques
Osteomyelitis / diagnosis
Osteomyelitis / immunology
Osteomyelitis / microbiology*
Osteomyelitis / therapy
Rituximab / adverse effects*
Shoulder Joint / surgery
Synovial Fluid
Therapeutic Irrigation
Ureaplasma urealyticum / isolation & purification*
Young Adult

Substances

Immunologic Factors
Rituximab
Doxycycline