Widespread rash as initial presentation of acute hepatitis E in a woman with well-controlled HIV

Rachel Pringle; Clare van Halsema

doi:10.1177/0956462420984697

Widespread rash as initial presentation of acute hepatitis E in a woman with well-controlled HIV

Int J STD AIDS. 2021 Jun;32(7):671-673. doi: 10.1177/0956462420984697. Epub 2021 Feb 3.

Authors

Rachel Pringle¹, Clare van Halsema¹

Affiliation

¹ Department of Infectious Diseases and Tropical Medicine, 156778North Manchester General Hospital, Manchester, UK.

PMID: 33530880
DOI: 10.1177/0956462420984697

Abstract

Sporadic, acute hepatitis E is increasingly common in the United Kingdom, associated with travel or locally acquired. A 45-year-old woman with well-controlled HIV presented with a widespread, polymorphic rash and transaminitis. Acute genotype 3 hepatitis E infection was confirmed and resolved without intervention. A review of the literature reveals a number of atypical presentations of acute autochthonous hepatitis E. Clinicians should consider testing for hepatitis E in the presence of nonspecific symptoms and deranged liver function tests.

Keywords: HEV; Hepatitis E; hepatitis; human immunodeficiency virus; infectious diseases; rash.

Publication types

Case Reports
Review

MeSH terms

Exanthema* / etiology
Female
Genotype
HIV Infections* / complications
HIV Infections* / diagnosis
HIV Infections* / drug therapy
Hepatitis E virus*
Hepatitis E* / diagnosis
Hepatitis E* / drug therapy
Humans
Middle Aged