Agammaglobulinemia with normal B-cell numbers in a patient lacking Bob1

Affiliations

• ¹ Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; University of Freiburg, Faculty of Biology, Freiburg, Germany.
• ² University of Freiburg, Faculty of Biology, Freiburg, Germany; Department of Rheumatology and Clinical Immunology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
• ³ Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
• ⁴ Department of Rheumatology and Clinical Immunology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
• ⁵ Division of Neuropediatrics and Muscular Disorders, Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, University Medical Center, University of Freiburg, Germany.
• ⁶ Department of Neuropediatrics, Children's Hospital, University Medical Center Schleswig-Holstein, University of Kiel, Kiel, Germany.
• ⁷ Department of Neuropediatrics, Children's Hospital, University Medical Center Schleswig-Holstein, University of Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
• ⁸ Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, Pa; The Epilepsy NeuroGenetics Initiative, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Biomedical and Health Informatics (DBHi), Children's, Hospital of Philadelphia, Philadelphia, Pa; Department of Neurology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pa.
• ⁹ CIRI, Université de Lyon, INSERM U1111, ENS de Lyon, Université Lyon, CNRS, UMR 5308, Lyon, France; Université Côte d'Azur, INSERM, C3M, Nice, France.
• ¹⁰ Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), the Medical Center, Faculty of Medicine, University of Freiburg, Germany.
• ¹¹ Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
• ¹² Medical Center Mrcheveli, Tbilisi, Georgia.
• ¹³ Institute of Molecular Health Sciences, ETH Zürich, Zürich, Switzerland.
• ¹⁴ Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: [email protected].
• ¹⁵ Department of Rheumatology and Clinical Immunology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Germany. Electronic address: [email protected].