Analyzing magnetic resonance imaging data from glioma patients using deep learning

Comput Med Imaging Graph. 2021 Mar:88:101828. doi: 10.1016/j.compmedimag.2020.101828. Epub 2020 Dec 2.

Abstract

The quantitative analysis of images acquired in the diagnosis and treatment of patients with brain tumors has seen a significant rise in the clinical use of computational tools. The underlying technology to the vast majority of these tools are machine learning methods and, in particular, deep learning algorithms. This review offers clinical background information of key diagnostic biomarkers in the diagnosis of glioma, the most common primary brain tumor. It offers an overview of publicly available resources and datasets for developing new computational tools and image biomarkers, with emphasis on those related to the Multimodal Brain Tumor Segmentation (BraTS) Challenge. We further offer an overview of the state-of-the-art methods in glioma image segmentation, again with an emphasis on publicly available tools and deep learning algorithms that emerged in the context of the BraTS challenge.

Keywords: BraTS; Brain tumor; Brain tumor segmentation challenge; Deep learning; Glioma; Image quantification; Image segmentation; Machine learning; NeuroOncology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Algorithms
  • Brain Neoplasms* / diagnostic imaging
  • Deep Learning*
  • Glioma* / diagnostic imaging
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Neural Networks, Computer