Understanding Substance use Policies and Associated Ethical Concerns: A survey of Pediatric Transplant Centers

Pediatr Transplant. 2021 Jun;25(4):e13984. doi: 10.1111/petr.13984. Epub 2021 Feb 12.

Abstract

Psychosocial risk factors, such as substance use, have been linked to poor post-transplant outcomes for solid organ transplant patients, including poor medication adherence, increased risk for rejection, and even graft failure. Despite universal consensus that substance use is an increasing problem among youth, many pediatric transplant centers do not have policies in place to address substance use and no universal guidelines exist regarding assessment during the pre-transplant evaluation in this population. An online survey was administered via REDCap™ and directed toward medical leaders (ie, medical and surgical directors) of national heart, kidney, and liver transplant centers. Questions examined the following: perspectives on the need for a universal transplant center policy on pediatric substance use, abuse, and dependence; timing and frequency of evaluation for substance use; specific substances which would elicit respondents' concerns; and ethical concerns surrounding substance use. Data were analyzed using descriptive statistics. Data were collected from 52 respondents from 38 transplant centers, with the majority (n = 40; 77%) reporting no substance use policy in place for pediatric transplant patients. However, many endorsed concerns if a pediatric patient was found to be using specific substances. Our findings further highlight the need for a universal substance use policy across pediatric solid organ transplant centers. The results from the distributed survey will help to provide guidelines and best practices when establishing a universal policy for substance use.

Keywords: ethics; pediatric transplant; policy; substance abuse; substance use.

MeSH terms

  • Adolescent
  • Attitude of Health Personnel*
  • Child
  • Child, Preschool
  • Health Care Surveys
  • Humans
  • Infant
  • Infant, Newborn
  • Organ Transplantation* / ethics
  • Organ Transplantation* / standards
  • Organizational Policy*
  • Patient Selection* / ethics
  • Practice Guidelines as Topic*
  • Preoperative Care / ethics
  • Preoperative Care / methods*
  • Preoperative Care / standards
  • Substance-Related Disorders* / complications
  • Substance-Related Disorders* / diagnosis
  • United States