A rare case of acquired factor V inhibitor, during treatment with dabigatran for chronic atrial fibrillation, successfully treated with bypassing agents

Gaetano Giuffrida; Uros Markovic; Daniela Nicolosi; Valeria Calafiore

doi:10.1002/ccr3.3586

A rare case of acquired factor V inhibitor, during treatment with dabigatran for chronic atrial fibrillation, successfully treated with bypassing agents

Clin Case Rep. 2020 Dec 2;9(2):623-628. doi: 10.1002/ccr3.3586. eCollection 2021 Feb.

Authors

Gaetano Giuffrida^{1

2}, Uros Markovic^{1

2}, Daniela Nicolosi^{1

2}, Valeria Calafiore^{1

2}

Affiliations

¹ Division of Hematology AOU "Policlinico - Vittorio Emanuele" Catania Italy.
² Department of General Surgery and Medical-Surgical Specialties, Hematology Section University of Catania Catania Italy.

Abstract

Acquired factor V inhibitor represents a rare condition, described only in case reports. The use of activated bypassing agents in bleeding control could be of aid and improve the survival in symptomatic patients with acquired factor V inhibitor.

Keywords: acquired coagulation inhibitor; bypassing agents; dabigatran; factor V; immunosuppressive therapy.

Publication types

Case Reports