Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Dengjie Yu; Zijun Cai; Daishi Li; Yi Zhang; Miao He; Yuntao Yang; Di Liu; Wenqing Xie; Yusheng Li; Wenfeng Xiao

doi:10.1155/2021/8884283

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Stem Cells Int. 2021 Feb 4:2021:8884283. doi: 10.1155/2021/8884283. eCollection 2021.

Authors

Dengjie Yu^{1

2}, Zijun Cai^{1

2}, Daishi Li³, Yi Zhang^{1

2}, Miao He^{1

2}, Yuntao Yang^{1

2}, Di Liu^{1

2}, Wenqing Xie^{1

2}, Yusheng Li^{1

2}, Wenfeng Xiao^{1

2}

Affiliations

¹ Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China.
³ Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Abstract

Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.

Publication types

Review