Pineal alveolar rhabdomyosarcoma with PAX3:NCOA2 fusion inducing OLIG2 expression, a potential pitfall in the central nervous system

Histopathology. 2021 Sep;79(3):437-439. doi: 10.1111/his.14364. Epub 2021 Jun 24.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / cerebrospinal fluid
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / genetics
  • Brain Neoplasms / metabolism
  • Brain Neoplasms / pathology*
  • Central Nervous System / pathology
  • Child
  • Diagnosis, Differential
  • Gene Expression Regulation, Neoplastic / genetics
  • Glioma / diagnosis
  • Glioma / pathology
  • Humans
  • Intracranial Hypertension
  • Male
  • Nuclear Receptor Coactivator 2 / genetics
  • Nuclear Receptor Coactivator 2 / metabolism
  • Oligodendrocyte Transcription Factor 2 / metabolism
  • Oncogene Proteins, Fusion / genetics
  • PAX3 Transcription Factor / genetics
  • PAX3 Transcription Factor / metabolism
  • Pineal Gland / pathology*
  • Rhabdomyosarcoma, Alveolar / diagnosis
  • Rhabdomyosarcoma, Alveolar / genetics
  • Rhabdomyosarcoma, Alveolar / metabolism
  • Rhabdomyosarcoma, Alveolar / pathology*

Substances

  • Biomarkers, Tumor
  • NCOA2 protein, human
  • Nuclear Receptor Coactivator 2
  • OLIG2 protein, human
  • Oligodendrocyte Transcription Factor 2
  • Oncogene Proteins, Fusion
  • PAX3 Transcription Factor