Reducing cervical cancer deaths in women living with HIV: PEPFAR and the Go Further partnership

Prev Med. 2021 Mar:144:106295. doi: 10.1016/j.ypmed.2020.106295. Epub 2021 Mar 4.

Abstract

Women with HIV bear a significant burden of Human Papillomavirus (HPV) related cervical disease, and a have a higher risk of dying from cervical cancer should it occur. WLH have increased acquisition of HPV and decreased clearance, leading to persistent HPV infection: a risk for cervical cancer. The greatest burden of HIV in women occurs in sub-Saharan Africa where diagnostic and treatment services for cervical disease are limited. This paper will describe the epidemiology of HPV related cervical disease in women living with HIV (WLH) and the efforts to treat precursor lesions in HIV treatment programs supported by the President's Emergency Plan for AIDS Relief (PEPFAR.

Keywords: Cervical cancer prevention; HIV; HPV; PEPFAR; Resource limited settings; Subsaharan Africa; VIA; Women's health.

Publication types

  • Review

MeSH terms

  • Africa South of the Sahara / epidemiology
  • Female
  • HIV Infections* / drug therapy
  • Humans
  • Papillomaviridae
  • Papillomavirus Infections*
  • Uterine Cervical Neoplasms* / prevention & control