Malnutrition and related factors in Filipino patients with Parkinson's disease: results from a pilot study

Neurodegener Dis Manag. 2021 Apr;11(2):125-135. doi: 10.2217/nmt-2020-0050. Epub 2021 Mar 11.

Abstract

Aim: Emerging evidence demonstrates a bidirectional relationship between nutritional status and Parkinson's disease (PD). Our aim was to determine the local prevalence of malnutrition and associated factors among Filipino PD patients. Materials & methods: We assessed the nutritional status of 95 PD patients using the body mass index (BMI) and Subjective Global Assessment (SGA) and identified malnutrition-associated factors. Results & conclusion: In our sample, the mean BMI was 24.5 ± 4.2 kg/m2. Consistent with published estimates, five (5.3%) patients were classified as underweight and 57 (60%) patients were classified as overweight/obese. A total of 30 (31.6%) patients had abnormal nutritional status based on SGA. Weight-adjusted levodopa equivalent daily dose was a significant factor (p = 0.032) for BMI, while dysphagia and higher weight-adjusted levodopa equivalent daily dose were found to be predictive of abnormal nutritional status using SGA (adjusted odds ratio of 8.85 [95% CI: 1.59-49.17; p = 0.015] and 1.10 [95% CI: 1.02-1.20; p = 0.021], respectively).

Keywords: Parkinson’s disease; body mass index; nutritional status; subjective global assessment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Body Mass Index
  • Cross-Sectional Studies
  • Female
  • Humans
  • Levodopa / adverse effects
  • Male
  • Malnutrition / epidemiology*
  • Middle Aged
  • Nutritional Status
  • Parkinson Disease / complications*
  • Philippines / epidemiology
  • Pilot Projects
  • Prevalence

Substances

  • Levodopa