To Vaccinate or not: Influenza Virus and Lung Cancer Progression

Trends Cancer. 2021 Jul;7(7):573-576. doi: 10.1016/j.trecan.2021.02.006. Epub 2021 Mar 10.

Abstract

Influenza virus infection leads to severe and complicated disease, particularly in patients with lung cancer. It alters the tumor microenvironment (TME), which may potentiate lung cancer progression and disrupt responses to antitumoral treatments. Consequently, influenza vaccination and antiviral treatments should be recommended to all patients with lung cancer.

Keywords: cancer patients; influenza virus; lung cancer; vaccination.

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Disease Progression
  • Humans
  • Influenza A virus / immunology*
  • Influenza Vaccines / administration & dosage*
  • Influenza, Human / complications
  • Influenza, Human / immunology
  • Influenza, Human / therapy*
  • Influenza, Human / virology
  • Lung / immunology
  • Lung / pathology
  • Lung / virology
  • Lung Neoplasms / complications
  • Lung Neoplasms / immunology
  • Lung Neoplasms / mortality*
  • Lung Neoplasms / pathology
  • Medical Oncology / standards
  • Practice Guidelines as Topic
  • Tumor Microenvironment / immunology
  • Vaccination / standards

Substances

  • Antiviral Agents
  • Influenza Vaccines