Adherence to Public Health Measures Mitigates the Risk of COVID-19 Infection in Older Adults: A Community-Based Study

Mayo Clin Proc. 2021 Apr;96(4):912-920. doi: 10.1016/j.mayocp.2020.12.016. Epub 2020 Dec 28.

Abstract

Objective: To assess the prevalence and characteristics of coronavirus disease 2019 (COVID-19) cases during the reopening period in older adults, given that little is known about the prevalence of COVID-19 after the stay-at-home order was lifted in the United States, nor the actual effects of adherence to recommended public health measures (RPHM) on the risk of COVID-19.

Patients and methods: This was a cross-sectional study nested in a parent prospective cohort study, which followed a population-based sample of 2325 adults 50 years and older residing in southeast Minnesota to assess the incidence of viral infections. Participants were instructed to self-collect both nasal and oropharyngeal swabs, which were tested by reverse transcription polymerase chain reaction-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) assay between May 8, 2020, and June, 30, 2020. We assessed the prevalence of COVID-19 cases and characteristics of study subjects.

Results: A total of 1505 eligible subjects participated in the study whose mean age was 68 years, with 885 (59%) women, 32 (2%) racial/ethnic minorities, and 906 (60%) with high-risk conditions for influenza. The prevalence of other Coronaviridae (human coronavirus [HCoV]-229E, HCoV-NL63, and HCoV-OC43) during the 2019 to 2020 flu season was 109 (7%), and none tested positive for SARS-CoV-2. Almost all participants reported adhering to the RPHM (1,488 [99%] for social distancing, 1,438 [96%] for wearing mask in a public space, 1,476 [98%] for hand hygiene, and 1,441 (96%) for staying home mostly). Eighty-six percent of participants resided in a single-family home.

Conclusion: We did not identify SARS-COV-2 infection in our study cohort. The combination of participants' behavior in following the RPHM and their living environment may considerably mitigate the risk of COVID-19.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • COVID-19 Testing / methods
  • COVID-19 Testing / statistics & numerical data
  • COVID-19* / diagnosis
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • COVID-19* / psychology
  • Communicable Disease Control* / methods
  • Communicable Disease Control* / organization & administration
  • Communicable Disease Control* / statistics & numerical data
  • Cross-Sectional Studies
  • Disease Transmission, Infectious / prevention & control
  • Female
  • Guideline Adherence / statistics & numerical data*
  • Humans
  • Male
  • Minnesota / epidemiology
  • Physical Distancing*
  • Prevalence
  • Public Health* / methods
  • Public Health* / statistics & numerical data
  • Risk Reduction Behavior
  • Universal Precautions / methods
  • Universal Precautions / statistics & numerical data
  • Virology / methods