Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey

Dig Liver Dis. 2021 Jun;53(6):682-688. doi: 10.1016/j.dld.2021.02.021. Epub 2021 Mar 8.

Abstract

Background: The SARS-CoV-2 pandemic has had a huge impact on healthcare systems, resulting in many routine diagnostic procedures either being halted or postponed.

Aims: To evaluate whether the diagnoses of colorectal, gastric and pancreatic cancers have been impacted by the SARS-CoV-2 pandemic in Italy.

Methods: A survey designed to collect the number of histologically-proven diagnoses of the three cancers in gastroenterology services across Italy from January 1 to October 31 in 2017-2020. Non-parametric ANOVA for repeated measurements was applied to compare distributions by years and macro-areas.

Results: Compared to 2019, in 2020 gastric cancer diagnoses decreased by 15.9%, CRC by 11.9% and pancreatic by 9.9%. CRC distributions showed significant differences between all years, stomach cancer between 2018 and 2020 and 2019-2020, and pancreatic cancer only between 2017 and 2019. The 2019-2020 comparison showed fewer CRC diagnoses in the North (-13.7%), Center (-16.5%) and South (-4.1%), fewer stomach cancers in the North (-19.0%) and South (-9.4%), and fewer pancreatic cancers in the North (-14.1%) and Center (-4.7%), with an increase in the South (+12.3%). Distributions of CRC and gastric cancer were significantly different between all years in the North.

Conclusions: This survey highlights the concerning effects of the COVID-19 pandemic on the diagnostic yield of gastroenterology services for stomach, colorectal and pancreatic cancers in Italy.

Keywords: COVID-19; Colorectal cancer; Gastric cancer; Pancreatic cancer; SARS-CoV-2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Delivery of Health Care* / organization & administration
  • Delivery of Health Care* / trends
  • Diagnostic Techniques, Digestive System
  • Digestive System Neoplasms* / diagnosis
  • Digestive System Neoplasms* / epidemiology
  • Early Detection of Cancer* / methods
  • Early Detection of Cancer* / trends
  • Gastroenterology / methods
  • Gastroenterology / statistics & numerical data
  • Humans
  • Infection Control / methods
  • Italy / epidemiology
  • Organizational Innovation
  • SARS-CoV-2
  • Surveys and Questionnaires