Cytomegalovirus retinitis following dexamethasone intravitreal implant

Sarah G Chaudhry; Adrian T Fung

doi:10.1016/j.ajoc.2021.101055

Cytomegalovirus retinitis following dexamethasone intravitreal implant

Am J Ophthalmol Case Rep. 2021 Mar 4:22:101055. doi: 10.1016/j.ajoc.2021.101055. eCollection 2021 Jun.

Authors

Sarah G Chaudhry¹, Adrian T Fung^{1

2

3}

Affiliations

¹ Westmead Hospital, Westmead, Sydney, New South Wales, Australia.
² Westmead and Central Clinical Schools, Discipline of Clinical Ophthalmology and Eye Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, 2145, Australia.
³ Department of Ophthalmology, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, 2109, Australia.

Abstract

Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII).

Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved.

Conclusion and importance: DII can trigger CMV retinitis in immunocompetent patients.

Keywords: Cytomegalovirus (CMV); Dexamethasone intravitreal implant (DII); Immunocompetent; Retinitis.

Publication types

Case Reports